Essiac Çayı
Synopsis
Bu bölümde Essiac çayının olası bileşenleri, tarihi, kullanımıyla ilgili belirtiler, çalışmalar ve olası etkileri detaylıca ele alınmıştır., Essiac çayı, geleneksel kanser tedavilerine alternatif olarak kullanılan bir bitkisel karışımdır. Rene Caisse tarafından geliştirilen bu karışım, içeriğinde farklı bitkiler barındırıyor. Ancak, bilimsel olarak kanseri tedavi ettiği konusunda kesin bir kanıt bulunmamakla birlikte, bazı çalışmalar çeşitli etkiler göstermiş olsa da bu kanıtlar yeterli değil. Çalışmalar, bazı anti-kanser özelliklere işaret etse de bu kanıtlar eksik ve tartışmalıdır. Ayrıca, içerdiği bitkilerin bazıları potansiyel yan etkilere neden olabilir, bu nedenle dikkatli kullanım önerilmektedir. Essiac çayı genellikle besin takviyesi olarak satılır ve sağlıkla ilgili iddialarda bulunmak yerine genellikle sağlığı destekleyici bir ürün olarak tanıtılır.
This section extensively covers the potential components, history, indications related to the usage, studies, and potential effects of Essiac tea. Essiac tea is a herbal mixture used as an alternative to traditional cancer treatments. Developed by Rene Caisse, this blend contains various plants. However, while there isn't definitive scientific evidence supporting its ability to treat cancer, some studies have shown various effects, though these findings are insufficient. Studies indicate some anti-cancer properties, yet these findings are limited and debated. Additionally, some of its components may lead to potential side effects, hence careful usage is recommended. Essiac tea is generally marketed as a dietary supplement and is usually presented as a product supporting health rather than making specific health claims.
References
Kaegi E. Unconventional therapies for cancer: 1. Essiac. The Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. CMAJ 1998;158:897-902. Accessed 7th of September 2020.
Boon H, Wong J. Botanical medicine and cancer: a review of the safety and efficacy. Expert Opin Pharmacother 2004;5:2485-501. Accessed 7th of September 2020.
Tai J, Cheung S, Wong S, Lowe C. In vitro comparison of Essiac and Flor-Essence on human tumor cell lines. Oncol Rep 2004;11:471-6. Accessed 7th of September 2020.
Thomas R. The Essiac report: The True Story of a Canadian Herbal Cancer Remedy and of the Thousands of Lives it Continues to Save, 3rd ed. Los Angeles: Alternative Treatment Information Networks, 1993.
Meehan D, Agar J. Doctor’s license suspended; some patients still support him. The Grand Rapids Press, April 18th, 1997:12.
NIH National Cancer Institute. Essiac/Flor Essence PDQ. [Online documents]. Available online. Accessed 7th of September 2020.
Hutchinson DJ. Experimental Chemotherapy, Memorial Sloan-Kettering Cancer Center, Rye, N, personal communication, September 26, 1988 and March 1989
Glun GL. Essiac. Nature’s cure for cancer. Wildfire 1991:6:48-55.
Foldeak S, Dombradi GA. Tumor-Growth Inhibiting Substances of Plant Origin. I. Isolation of the Active Principle of Arctium lappa. Acta Phys Chem 1964;10:91- 93. Accessed 7th of September 2020
Dombradi CA, Foldeak S. Screening Report on the Antitumor Activity of Purified Arctium Lappa Extracts. Tumori 1966;52:173.
Itokawa H, Watanabe K, Mihara K. Screening Test for Antitumor Activity of Crude Drugs (2). Shoyakugaku Zasshi 1982;36:145-9.
Woo WS, Lee EB, Chang I. Biological Evaluation of Korean Medicinal Plants. II. Yakhak Hoe Chi 1977;21:177-183. Accessed 7th of September 2020.
Morita K, Kada T, Namiki M. A desmutagenic factor isolated from burdock (Arctium lappa Linne). Mutat Res 1984;129:25-31. Accessed 7th of September 2020.
US Congress, Office of Technology Assessment: Unconventional Cancer Treatments. Washington, DC: U.S. Government Printing Office, 1990. OTA-H-405, pp 71-5. Accessed 7th of September 2020
Belkin M, Fitzgerald DB. Tumor-Damaging Capacity of Plant Materials. 1. Plants Used as Cathartics. J Natl Cancer Inst 1952;13:139-155. Accessed 7th of September 2020
Kupchan SM, Karim A. Tumor inhibitors. 114. Aloe emodin: antileukemic principle isolated from Rhamnus frangula L. Lloydia 1976;39:223-4. Accessed 7th of September 2020.
Pettit GR, Blazer RM, Reierson DA. Antineoplastic agents. 51. The yellow jacket Vespula pensylvanica Lloydia 1977;40(3):247-52. Accessed 7th of September 2020.
Leonard BJ, Kennedy DA, Cheng FC, Chang KK, Seely D, Mills E: An in vivo analysis of the herbal compound essiac. Anticancer Res 2006; 26(4B):3057-3063. Accessed 7th of September 2020
Kulp KS, Montgomery JL, Nelson DO, Cutter B, Latham ER, Shattuck DL, Klotz DM, Bennett LM. Essiac and Flor-Essence herbal tonics stimulate the in vitro growth of human breast cancer cells. Breast Cancer Res Treat 2006; 98(3):249-59. Accessed 7th of September 2020.
Seely D, Kennedy DA, Myers SP, Cheras PA, Lin D, Li R, Cattley T, Brent PA, Mills E, Leonard BJ: In vitro analysis of the herbal compound Essiac. Anticancer Res 2007; 27(6B):3875-3882. Accessed 7th of September 2020
Eberding A, Madera C, Xie S, Wood CA, Brown PN, Guns ES: Evaluation of the antiproliferative effects of Essiac on in vitro and in vivo models of prostate cancer compared to paclitaxel. Nutr Cancer 2007; 58(2):188-196. Accessed 7th of September 2020
Henderson IWD. Director, Bureau of Human Prescription Drugs, Health Protection Branch, Health and Welfare Canada, Vanier, Ontario. Letter to J.W. Meakin. Executive Director, Ontario Cancer Treatment and Research Foundation, Toronto, Ontario, November 19th 1982. Summary
Boon H. Use of complementary / alternative medicine by breast cancer survivors in Ontario: Prevalence and perceptions. J Clin Oncol 2000;18:2515 – 2521. Accessed 7th of September 2020.
Low Dog T. Traditional and alternative therapies for breast cancer. Altern Ther Health Med 2001; 7:36-47. Accessed 7th of September 2020.
Tamayo C, Richardson M. Presentation at 36th Annual Drug Information Association Meeting. Baltimore, MD, June 17-21, 1999.
Morita H, et al. Cytotoxic and mutagenic effects of emodin on cultured mouse carcinoma FM3A cells. Mutat Res 1988;204:329-32. Accessed 7th of September 2020.
Zick SM, Sen A, Feng Y, Green J, Olatunde S, Boon H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med. 2006 Dec;12(10):971-80. doi: 10.1089/acm.2006.12.971. PMID: 17212569.
Ulbricht C, Weissner W, Hashmi S, Rae Abrams T, Dacey C, Giese N, Hammerness P, Hackman DA, Kim J, Nealon A, Voloshin R. Essiac: systematic review by the natural standard research collaboration. J Soc Integr Oncol 2009;7(2):73-80. Accessed 7th of September 2020.
Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5. Accessed 7th of September 2020.
Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998. Accessed 7th of September 2020.
Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. Accessed 7th of September 2020.
Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998. Accessed 7th of September 2020.
McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Bolton-Smith C, Price RJ, Fenton ST, et al. Compilation of a provisional UK database for the phylloquinone (vitamin K1) content of foods. Br J Nutr 2000;83:389-99. Accessed 7th of September 2020
Tice J, Cummings SR, Ettinger B, et al. Few adverse effects of two red clover extracts rich in phytoestrogens: a multicenter, placebo-controlled trial. Alt Ther Health Med 2001;7:S33.
Nelsen J, Barrette E, Tsouronix C, et al. Red clover (Trifolium pratense) monograph: A clinical decision support tool. J Herbal Pharmacotherapy 2002;2:49-72. Accessed 7th of September 2020.
This P, De La Rochefordiere A, Clough K, et al. Phytoestrogens after breast cancer. Endocr Relat Cancer 2001;8:129-34. Accessed 7th of September 2020.
Baker DH. Iodine toxicity and its amelioration. Exp Biol Med (Maywood) 2004;229:473-8. Accessed 7th of September 2020.
Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. Accessed 7th of September 2020.
Boon H, Wong J. Botanical medicine and cancer: a review of the safety and efficacy. Expert Opin Pharmacother 2004;5:2485-501. Accessed 7th of September 2020.
Tai J, Cheung S, Wong S, Lowe C. In vitro comparison of Essiac and Flor-Essence on human tumor cell lines. Oncol Rep 2004;11:471-6. Accessed 7th of September 2020.
Thomas R. The Essiac report: The True Story of a Canadian Herbal Cancer Remedy and of the Thousands of Lives it Continues to Save, 3rd ed. Los Angeles: Alternative Treatment Information Networks, 1993.
Meehan D, Agar J. Doctor’s license suspended; some patients still support him. The Grand Rapids Press, April 18th, 1997:12.
NIH National Cancer Institute. Essiac/Flor Essence PDQ. [Online documents]. Available online. Accessed 7th of September 2020.
Hutchinson DJ. Experimental Chemotherapy, Memorial Sloan-Kettering Cancer Center, Rye, N, personal communication, September 26, 1988 and March 1989
Glun GL. Essiac. Nature’s cure for cancer. Wildfire 1991:6:48-55.
Foldeak S, Dombradi GA. Tumor-Growth Inhibiting Substances of Plant Origin. I. Isolation of the Active Principle of Arctium lappa. Acta Phys Chem 1964;10:91- 93. Accessed 7th of September 2020
Dombradi CA, Foldeak S. Screening Report on the Antitumor Activity of Purified Arctium Lappa Extracts. Tumori 1966;52:173.
Itokawa H, Watanabe K, Mihara K. Screening Test for Antitumor Activity of Crude Drugs (2). Shoyakugaku Zasshi 1982;36:145-9.
Woo WS, Lee EB, Chang I. Biological Evaluation of Korean Medicinal Plants. II. Yakhak Hoe Chi 1977;21:177-183. Accessed 7th of September 2020.
Morita K, Kada T, Namiki M. A desmutagenic factor isolated from burdock (Arctium lappa Linne). Mutat Res 1984;129:25-31. Accessed 7th of September 2020.
US Congress, Office of Technology Assessment: Unconventional Cancer Treatments. Washington, DC: U.S. Government Printing Office, 1990. OTA-H-405, pp 71-5. Accessed 7th of September 2020
Belkin M, Fitzgerald DB. Tumor-Damaging Capacity of Plant Materials. 1. Plants Used as Cathartics. J Natl Cancer Inst 1952;13:139-155. Accessed 7th of September 2020
Kupchan SM, Karim A. Tumor inhibitors. 114. Aloe emodin: antileukemic principle isolated from Rhamnus frangula L. Lloydia 1976;39:223-4. Accessed 7th of September 2020.
Pettit GR, Blazer RM, Reierson DA. Antineoplastic agents. 51. The yellow jacket Vespula pensylvanica Lloydia 1977;40(3):247-52. Accessed 7th of September 2020.
Leonard BJ, Kennedy DA, Cheng FC, Chang KK, Seely D, Mills E: An in vivo analysis of the herbal compound essiac. Anticancer Res 2006; 26(4B):3057-3063. Accessed 7th of September 2020
Kulp KS, Montgomery JL, Nelson DO, Cutter B, Latham ER, Shattuck DL, Klotz DM, Bennett LM. Essiac and Flor-Essence herbal tonics stimulate the in vitro growth of human breast cancer cells. Breast Cancer Res Treat 2006; 98(3):249-59. Accessed 7th of September 2020.
Seely D, Kennedy DA, Myers SP, Cheras PA, Lin D, Li R, Cattley T, Brent PA, Mills E, Leonard BJ: In vitro analysis of the herbal compound Essiac. Anticancer Res 2007; 27(6B):3875-3882. Accessed 7th of September 2020
Eberding A, Madera C, Xie S, Wood CA, Brown PN, Guns ES: Evaluation of the antiproliferative effects of Essiac on in vitro and in vivo models of prostate cancer compared to paclitaxel. Nutr Cancer 2007; 58(2):188-196. Accessed 7th of September 2020
Henderson IWD. Director, Bureau of Human Prescription Drugs, Health Protection Branch, Health and Welfare Canada, Vanier, Ontario. Letter to J.W. Meakin. Executive Director, Ontario Cancer Treatment and Research Foundation, Toronto, Ontario, November 19th 1982. Summary
Boon H. Use of complementary / alternative medicine by breast cancer survivors in Ontario: Prevalence and perceptions. J Clin Oncol 2000;18:2515 – 2521. Accessed 7th of September 2020.
Low Dog T. Traditional and alternative therapies for breast cancer. Altern Ther Health Med 2001; 7:36-47. Accessed 7th of September 2020.
Tamayo C, Richardson M. Presentation at 36th Annual Drug Information Association Meeting. Baltimore, MD, June 17-21, 1999.
Morita H, et al. Cytotoxic and mutagenic effects of emodin on cultured mouse carcinoma FM3A cells. Mutat Res 1988;204:329-32. Accessed 7th of September 2020.
Zick SM, Sen A, Feng Y, Green J, Olatunde S, Boon H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med. 2006 Dec;12(10):971-80. doi: 10.1089/acm.2006.12.971. PMID: 17212569.
Ulbricht C, Weissner W, Hashmi S, Rae Abrams T, Dacey C, Giese N, Hammerness P, Hackman DA, Kim J, Nealon A, Voloshin R. Essiac: systematic review by the natural standard research collaboration. J Soc Integr Oncol 2009;7(2):73-80. Accessed 7th of September 2020.
Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5. Accessed 7th of September 2020.
Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998. Accessed 7th of September 2020.
Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. Accessed 7th of September 2020.
Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998. Accessed 7th of September 2020.
McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Bolton-Smith C, Price RJ, Fenton ST, et al. Compilation of a provisional UK database for the phylloquinone (vitamin K1) content of foods. Br J Nutr 2000;83:389-99. Accessed 7th of September 2020
Tice J, Cummings SR, Ettinger B, et al. Few adverse effects of two red clover extracts rich in phytoestrogens: a multicenter, placebo-controlled trial. Alt Ther Health Med 2001;7:S33.
Nelsen J, Barrette E, Tsouronix C, et al. Red clover (Trifolium pratense) monograph: A clinical decision support tool. J Herbal Pharmacotherapy 2002;2:49-72. Accessed 7th of September 2020.
This P, De La Rochefordiere A, Clough K, et al. Phytoestrogens after breast cancer. Endocr Relat Cancer 2001;8:129-34. Accessed 7th of September 2020.
Baker DH. Iodine toxicity and its amelioration. Exp Biol Med (Maywood) 2004;229:473-8. Accessed 7th of September 2020.
Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. Accessed 7th of September 2020.
Pages
63-68
Published
March 11, 2024
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1.
Safarov S. Essiac Çayı. In: Sakin A, editor. Kanser Hastalarının Başvurduğu Geleneksel ve Tamamlayıcı Tedaviler - Tıbbi Onkolog Gözü ile Bakış ve Onkolojik İlaçlarla Etkileşim [Internet]. Türkiye: Academician Publishing Book DOI Portal; 2024 [cited 2026 Jul. 13]. pp. 63-8. Available from: https://www.omp35.books.akademisyen.net/index.php/akya/catalog/book/2380/chapter/13890
