Balık Yağı / Omega Yağları
Özet
İmmunonütrisyon olarak bilinen glutamin, arjinin, omega-3 yağ asitleri ve diğer substrastlar insan sağlığı için önemlidir. Bu maddeler inflamatuar yanıtı, bağırsak sistemi ve immun foknsiyonları düzenlemektedir. İmmun yanit diğer hastalıklarda olduğu gibi kanserle savaşta da önemli yer almaktadır. İmmun sistemi güçlendirerek regüle edilmesi kanser hastalıklarında da tedavinin ek parçasıdır. Birçok hastalıkta (travma, yanık, inflamatuar hastalıklar) farklı randomize kontrollü çalışma yapılsa da, kanser hastalıklarında güçlü veriler henüz azdır. Bu yazıda amacımız kanser ile balık yağı ilişkisini araştırmaktır.
Glutamate, arginine, omega-3 fatty acids, and other substrates are crucial for human health and are referred to as immunonutrition. These substances regulate inflammatory enemy, gastrointestinal system and immune functions. Immune response plays an important role in the fight against cancer, as in other disease. It is an additional unit of organs in cancer cells to regulate the immune system by strengthening it. t cancer. In cancer cells, the immune system is controlled by an extra organ system that is strengthened. Although different randomized controlled studies have been conducted in many diseases (trauma, burns, inflammatory diseases), strong datas are not yet available in cancer. Our aim in this article is to investigate the relationship between cancer and fish oil.
Referanslar
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K. N. H. Tayar M, “Beslenme ve sağlıklı yaşam,” 2004.
N. M. Zatsick and P. Mayket, “Fish Oil: Getting to the Heart of It,” The Journal for Nurse Practitioners, vol. 3, no. 2, pp. 104–109, Feb. 2007, doi: 10.1016/j.nurpra.2006.09.003.
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J.-M. Bourre, “Dietary omega-3 fatty acids for women,” Biomedicine & Pharmacotherapy, vol. 61, no. 2–3, pp. 105–112, Feb. 2007, doi: 10.1016/j.biopha.2006.09.015.
N. Kromann and A. Green, “Epidemiological studies in the Upernavik district, Greenland. Incidence of some chronic diseases 1950-1974.,” Acta Med Scand, vol. 208, no. 5, pp. 401–6, 1980.
F. S. von S. C. L. R. S. T. Weber PC, “Dietary omega-3 polyunsaturated fatty acids and eicosanoid formation in man. In Simopoulos AP, Kifer RR, Martin RE (eds): ‘Health Effects of Polyunsaturated Fatty Acids in Seafoods.’ ,” Orlando: Academic Press, pp 49–60, 1986., 1986.
L. T. A. K. Lewis RA, “Effects of omega-3 fatty acids on the generation of products of the 5-lipoxygenase pathway. In Simopoulos AP, Kifer RR, Martin RE (eds): ‘Health Effects of Polyunsaturated Fatty Acids in Seafoods.,’” Orlando, Academic Press, pp 227-238, 1986.
K. R. M. R. B. S. (eds) Simopoulos AP, “ ‘Health Effects of w3 Polyunsaturated Fatty Acids in Seafoods,’ ,” vol. 66, World Rev Nutr Diet. Basel: Karger, , 1991.
J. L. Breslow, “n−3 Fatty acids and cardiovascular disease,” Am J Clin Nutr, vol. 83, no. 6, pp. 1477S-1482S, Jun. 2006, doi: 10.1093/ajcn/83.6.1477S.
K. Vanschoonbeek et al., “Variable hypocoagulant effect of fish oil intake in humans: Modulation of fibrinogen level and thrombin generation,” Arterioscler Thromb Vasc Biol, vol. 24, no. 9, pp. 1734–1740, Sep. 2004, doi: 10.1161/01.ATV.0000137119.28893.0b.
Mol S, “Su Ürünleri Alternatif Ürün Sanayisi,” 2004.
G. Caughey, E. Mantzioris, R. Gibson, L. Cleland, and M. James, “The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil,” Am J Clin Nutr, vol. 63, no. 1, pp. 116–122, Jan. 1996, doi: 10.1093/ajcn/63.1.116.
J. M. McKenney and D. Sica, “Prescription omega-3 fatty acids for the treatment of hypertriglyceridemia,” American Journal of Health-System Pharmacy, vol. 64, no. 6, pp. 595–605, Mar. 2007, doi: 10.2146/ajhp060164.
W. S. Harris et al., “Safety and Efficacy of Omacor in Severe Hypertriglyceridemia,” European Journal of Cardiovascular Prevention & Rehabilitation, vol. 4, no. 5–6, pp. 385–391, Oct. 1997, doi: 10.1177/174182679700400511.
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M. M. de A. S. J. de S. F. M. N. E. de M. T. E. .Camargo CQ, “Fish oil supplementation during chemotherapy increases posterior time to tumor progression in colorectal cance,” 2016.
M. M. B. H. C. T. de S. F. M. de M. T. E. et al Camargo CQ, “Fish oil decreases the severity of treatment-related adverse events in gastrointestinal cancer patients undergoing chemotherapy: a randomized, placebo controlled, triple-blind control trial,” 2019.
L. J. S. M. S. S. P. M. S. E. et al Van der Meij BS, “Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT,” 2012.
D. A. O. D. D. J. S. A. C. D. et al Hamza N, “Perioperative enteral immunonutrition modulates systemic and mucosal immunity and the inflammatory response in patients with periampullary cancer scheduled for pancreaticoduodenectomy: a randomized clinical trial,” 2015.
J. E. Manson et al., “Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer,” New England Journal of Medicine, vol. 380, no. 1, pp. 23–32, Jan. 2019, doi: 10.1056/NEJMoa1811403.
R. P. Bazinet and S. Layé, “Polyunsaturated fatty acids and their metabolites in brain function and disease,” Nat Rev Neurosci, vol. 15, no. 12, pp. 771–785, Dec. 2014, doi: 10.1038/nrn3820.
C. Giordano, P. Plastina, I. Barone, S. Catalano, and D. Bonofiglio, “n–3 Polyunsaturated Fatty Acid Amides: New Avenues in the Prevention and Treatment of Breast Cancer,” Int J Mol Sci, vol. 21, no. 7, p. 2279, Mar. 2020, doi: 10.3390/ijms21072279.
R. A. Siddiqui, K. A. Harvey, Z. Xu, E. M. Bammerlin, C. Walker, and J. D. Altenburg, “Docosahexaenoic acid: A natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects,” BioFactors, vol. 37, no. 6, pp. 399–412, Nov. 2011, doi: 10.1002/biof.181.
Z. Liu et al., “Association between fish oil supplementation and cancer risk according to fatty fish consumption: A large prospective population‐based cohort study using <scp>UK</scp> Biobank,” Int J Cancer, vol. 150, no. 4, pp. 562–571, Feb. 2022, doi: 10.1002/ijc.33819.
Yaşar T, “Morina Karaciğer Yağından Enzimatik Hidroliz İle Dha’nın Zenginleştirilmesinde Enzim Miktarı Ve Sürenin Etkisi,” 2004.
P. M. Kris-Etherton, W. S. Harris, and L. J. Appel, “Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease,” Circulation, vol. 106, no. 21, pp. 2747–2757, Nov. 2002, doi: 10.1161/01.CIR.0000038493.65177.94.
W. S. Harris, “Extending the cardiovascular benefits of omega-3 fatty acids,” Curr Atheroscler Rep, vol. 7, no. 5, pp. 375–380, Sep. 2005, doi: 10.1007/s11883-005-0050-0.
K. N. H. Tayar M, “Beslenme ve sağlıklı yaşam,” 2004.
N. M. Zatsick and P. Mayket, “Fish Oil: Getting to the Heart of It,” The Journal for Nurse Practitioners, vol. 3, no. 2, pp. 104–109, Feb. 2007, doi: 10.1016/j.nurpra.2006.09.003.
Baysal A, “Beslenme,” 2002.
J.-M. Bourre, “Dietary omega-3 fatty acids for women,” Biomedicine & Pharmacotherapy, vol. 61, no. 2–3, pp. 105–112, Feb. 2007, doi: 10.1016/j.biopha.2006.09.015.
N. Kromann and A. Green, “Epidemiological studies in the Upernavik district, Greenland. Incidence of some chronic diseases 1950-1974.,” Acta Med Scand, vol. 208, no. 5, pp. 401–6, 1980.
F. S. von S. C. L. R. S. T. Weber PC, “Dietary omega-3 polyunsaturated fatty acids and eicosanoid formation in man. In Simopoulos AP, Kifer RR, Martin RE (eds): ‘Health Effects of Polyunsaturated Fatty Acids in Seafoods.’ ,” Orlando: Academic Press, pp 49–60, 1986., 1986.
L. T. A. K. Lewis RA, “Effects of omega-3 fatty acids on the generation of products of the 5-lipoxygenase pathway. In Simopoulos AP, Kifer RR, Martin RE (eds): ‘Health Effects of Polyunsaturated Fatty Acids in Seafoods.,’” Orlando, Academic Press, pp 227-238, 1986.
K. R. M. R. B. S. (eds) Simopoulos AP, “ ‘Health Effects of w3 Polyunsaturated Fatty Acids in Seafoods,’ ,” vol. 66, World Rev Nutr Diet. Basel: Karger, , 1991.
J. L. Breslow, “n−3 Fatty acids and cardiovascular disease,” Am J Clin Nutr, vol. 83, no. 6, pp. 1477S-1482S, Jun. 2006, doi: 10.1093/ajcn/83.6.1477S.
K. Vanschoonbeek et al., “Variable hypocoagulant effect of fish oil intake in humans: Modulation of fibrinogen level and thrombin generation,” Arterioscler Thromb Vasc Biol, vol. 24, no. 9, pp. 1734–1740, Sep. 2004, doi: 10.1161/01.ATV.0000137119.28893.0b.
Mol S, “Su Ürünleri Alternatif Ürün Sanayisi,” 2004.
G. Caughey, E. Mantzioris, R. Gibson, L. Cleland, and M. James, “The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil,” Am J Clin Nutr, vol. 63, no. 1, pp. 116–122, Jan. 1996, doi: 10.1093/ajcn/63.1.116.
J. M. McKenney and D. Sica, “Prescription omega-3 fatty acids for the treatment of hypertriglyceridemia,” American Journal of Health-System Pharmacy, vol. 64, no. 6, pp. 595–605, Mar. 2007, doi: 10.2146/ajhp060164.
W. S. Harris et al., “Safety and Efficacy of Omacor in Severe Hypertriglyceridemia,” European Journal of Cardiovascular Prevention & Rehabilitation, vol. 4, no. 5–6, pp. 385–391, Oct. 1997, doi: 10.1177/174182679700400511.
J. Silva, I. Souza, R. Silva, P. Tavares, F. Teixeira, and P. S. Sliva, “The triglyceride lowering effect of fish oils is affected by fish consumption,” Int J Cardiol, vol. 57, no. 1, pp. 75–80, Nov. 1996, doi: 10.1016/S0167-5273(96)02810-0.
B. P. B. V. B. N. B. H. B. F. et al. Arends J, “ESPEN guidelines on nutrition in cancer patients,” 2017.
W. E. Hardman, “(n-3) Fatty Acids and Cancer Therapy,” J Nutr, vol. 134, no. 12, pp. 3427S-3430S, Dec. 2004, doi: 10.1093/jn/134.12.3427S.
M. M. de A. S. J. de S. F. M. N. E. de M. T. E. .Camargo CQ, “Fish oil supplementation during chemotherapy increases posterior time to tumor progression in colorectal cance,” 2016.
M. M. B. H. C. T. de S. F. M. de M. T. E. et al Camargo CQ, “Fish oil decreases the severity of treatment-related adverse events in gastrointestinal cancer patients undergoing chemotherapy: a randomized, placebo controlled, triple-blind control trial,” 2019.
L. J. S. M. S. S. P. M. S. E. et al Van der Meij BS, “Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT,” 2012.
D. A. O. D. D. J. S. A. C. D. et al Hamza N, “Perioperative enteral immunonutrition modulates systemic and mucosal immunity and the inflammatory response in patients with periampullary cancer scheduled for pancreaticoduodenectomy: a randomized clinical trial,” 2015.
J. E. Manson et al., “Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer,” New England Journal of Medicine, vol. 380, no. 1, pp. 23–32, Jan. 2019, doi: 10.1056/NEJMoa1811403.
R. P. Bazinet and S. Layé, “Polyunsaturated fatty acids and their metabolites in brain function and disease,” Nat Rev Neurosci, vol. 15, no. 12, pp. 771–785, Dec. 2014, doi: 10.1038/nrn3820.
C. Giordano, P. Plastina, I. Barone, S. Catalano, and D. Bonofiglio, “n–3 Polyunsaturated Fatty Acid Amides: New Avenues in the Prevention and Treatment of Breast Cancer,” Int J Mol Sci, vol. 21, no. 7, p. 2279, Mar. 2020, doi: 10.3390/ijms21072279.
R. A. Siddiqui, K. A. Harvey, Z. Xu, E. M. Bammerlin, C. Walker, and J. D. Altenburg, “Docosahexaenoic acid: A natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects,” BioFactors, vol. 37, no. 6, pp. 399–412, Nov. 2011, doi: 10.1002/biof.181.
Z. Liu et al., “Association between fish oil supplementation and cancer risk according to fatty fish consumption: A large prospective population‐based cohort study using <scp>UK</scp> Biobank,” Int J Cancer, vol. 150, no. 4, pp. 562–571, Feb. 2022, doi: 10.1002/ijc.33819.
Yaşar T, “Morina Karaciğer Yağından Enzimatik Hidroliz İle Dha’nın Zenginleştirilmesinde Enzim Miktarı Ve Sürenin Etkisi,” 2004.
P. M. Kris-Etherton, W. S. Harris, and L. J. Appel, “Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease,” Circulation, vol. 106, no. 21, pp. 2747–2757, Nov. 2002, doi: 10.1161/01.CIR.0000038493.65177.94.
W. S. Harris, “Extending the cardiovascular benefits of omega-3 fatty acids,” Curr Atheroscler Rep, vol. 7, no. 5, pp. 375–380, Sep. 2005, doi: 10.1007/s11883-005-0050-0.
Sayfalar
289-292
Yayınlanan
11 Mart 2024
Telif Hakkı (c) 2024 Akademisyen Yayınevi Kitap Portalı
Lisans
LisansNasıl Atıf Yapılır
1.
Majidova N. Balık Yağı / Omega Yağları. Içinde: Sakin A, editör. Kanser Hastalarının Başvurduğu Geleneksel ve Tamamlayıcı Tedaviler - Tıbbi Onkolog Gözü ile Bakış ve Onkolojik İlaçlarla Etkileşim [Internet]. Türkiye: Akademisyen Yayınevi Kitap DOI Portalı; 2024 [a.yer 13 Temmuz 2026]. ss. 289-92. Erişim adresi: https://www.omp35.books.akademisyen.net/index.php/akya/catalog/book/2380/chapter/13930
